Effects of a standardized anesthetic protocol on hematologic variables in healthy cats

Marc P. Dhumeaux, Elisabeth CR Snead, Tasha Y. Epp, Susan M. Taylor, Anthony P. Carr, Ryan M. Dickinson, Marina L. Leis

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


This study evaluated the effects of an anesthetic protocol using intravenous ketamine and midazolam, and intramuscular buprenorphine on hematologic variables in cats. Twelve healthy adult cats had blood collected for a complete blood count before and after the induction of anesthesia. There were significant decreases in red blood cell counts, hemoglobin concentrations and hematocrits after the induction of anesthesia. On average, red blood cell counts and hematocrits decreased by 25%, and hemoglobin concentrations decreased by 24%. Based on hematocrit, 3/12 samples (25%) taken while the cats were anesthetized would have been interpreted as belonging to anemic patients while none of the cats would have been considered anemic before anesthesia. This study suggests that a complete blood count performed on blood taken under anesthesia with this anesthetic protocol should be interpreted cautiously in order to not make a false diagnosis of anemia.

Original languageEnglish (US)
Pages (from-to)701-705
Number of pages5
JournalJournal of Feline Medicine and Surgery
Issue number10
StatePublished - Oct 2012

Bibliographical note

Funding Information:
This study was supported by a grant from the Western College of Veterinary Medicine Companion Animal Health Fund.

Copyright 2013 Elsevier B.V., All rights reserved.

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