The study focuses on evaluating the effects of adding a cryoprotective agent (CPA) on the thermal properties of solutions. Preliminary results for Phosphate Buffered Saline (PBS) with glycerol at subzero temperatures are reported. A Differential Scanning Calorimeter (DSC) was used to measure the specific heat and to observe latent heat release. Cryomicroscopy was performed using a cryostage to control the cooling and heating rate of the sample and visually observe microscopic changes. The specific heat data obtained from the DSC is also used for predicting bulk thermal conductivity by a transient heat transfer model using a thermistor. Thermal properties measurement results show opposing trends prior to and after devitrification and melting events with respect to glycerol concentration.
|Original language||English (US)|
|Number of pages||2|
|Journal||American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD|
|State||Published - 2004|
|Event||2004 ASME International Mechanical Engineering Congress and Exposition, IMECE - Anaheim, CA, United States|
Duration: Nov 13 2004 → Nov 19 2004