Effects of a cryoprotective agent on thermal properties of solutions at subzero temperatures

Jeung Hwan Choi, Bumsoo Han, John C. Bischof

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations


The study focuses on evaluating the effects of adding a cryoprotective agent (CPA) on the thermal properties of solutions. Preliminary results for Phosphate Buffered Saline (PBS) with glycerol at subzero temperatures are reported. A Differential Scanning Calorimeter (DSC) was used to measure the specific heat and to observe latent heat release. Cryomicroscopy was performed using a cryostage to control the cooling and heating rate of the sample and visually observe microscopic changes. The specific heat data obtained from the DSC is also used for predicting bulk thermal conductivity by a transient heat transfer model using a thermistor. Thermal properties measurement results show opposing trends prior to and after devitrification and melting events with respect to glycerol concentration.

Original languageEnglish (US)
Article numberIMECE2004-61576
Pages (from-to)767-768
Number of pages2
JournalAmerican Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD
Issue number1
StatePublished - 2004
Event2004 ASME International Mechanical Engineering Congress and Exposition, IMECE - Anaheim, CA, United States
Duration: Nov 13 2004Nov 19 2004


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