Effectiveness of BNT162b2 and mRNA-1273 Second Doses and Boosters for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and SARS-CoV-2-Related Hospitalizations: A Statewide Report From the Minnesota Electronic Health Record Consortium

Paul E Drawz, Malini DeSilva, Peter Bodurtha, Gabriela Vazquez Benitez, Anne M Murray, Alanna M. Chamberlain, R. Adams Dudley, Stephen Waring, Anupam B. Kharbanda, Daniel P Murphy, Miriam Halstead Muscoplat, Victor Melendez, Karen L Margolis, Lynn McFarling, Roxana Lupu, Tyler N Winkelman, Steve Johnson

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Using vaccine data combined with electronic health records, we report that mRNA boosters provide greater protection than a 2-dose regimen against SARS-CoV-2 infection and related hospitalizations. The benefit of a booster was more evident in the elderly and those with comorbidities.

Original languageEnglish (US)
Pages (from-to)890-892
Number of pages3
JournalClinical Infectious Diseases
Volume75
Issue number5
DOIs
StatePublished - Sep 1 2022

Bibliographical note

Publisher Copyright:
© The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Keywords

  • COVID-19
  • SARS-CoV-2
  • booster
  • hospitalization
  • vaccine

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