Effect of the LoBAG30 diet on blood glucose control in people with type 2 diabetes

Frank Q. Nuttall, Kelly Schweim, Heidi Hoover, Mary C. Gannon

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


In subjects with untreated type 2 diabetes, we previously determined that a weight-maintenance, non-ketogenic diet containing 30:60;% protein, 50160% fat and 20% carbohydrate (30:50:20) decreased the percentage total glycohaemoglobin (%tGHb) by 2-2% glycohaemoglobin over 5 weeks compared to a diet recommended for the American public (protein - fat - carbohydrate 15:30:55). Both the fasting and postprandial glucose were decreased. The objective of the present study was to determine if increasing the carbohydrate content from 20 to 30% at the expense of fat would still provide a similar effect on %tGHb, fasting and postprandial glucose concentration. Eight men with untreated type 2 diabetes were studied over a 5-week period. Results at the beginning (standard diet) and end of the 5-week study were analysed. Body weight was stable. Fasting glucose concentration decreased by 40 24 h glucose area response decreased by 45%. Insulin did not change. Mean %tGHb decreased by 1-7 (from 10-8 to 9-1%), and was still decreasing linearly at 5 weeks. In conclusion, a high-protein, 30% carbohydrate diet could be a patient-empowering method of improving the hyperglycaemia of type 2 diabetes without pharmacologic intervention. Long-term effects and general applicability of this diet remain to be determined.

Original languageEnglish (US)
Pages (from-to)511-519
Number of pages9
JournalBritish Journal of Nutrition
Issue number3
StatePublished - Mar 2008
Externally publishedYes


  • Glycaemic index
  • Glycohaemoglobin
  • High-protein diet
  • Insulin


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