Effect of nicotine on in vitro human sperm penetrability through cervical mucus and motility parameters

L. A. Crandall, H. C. Hensleigh, W. R. Phipps

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Nicotine at concentrations found in the cervical mucus of female smokers appeared to enhance in vitro human sperm penetrability through ovulatory bovine cervical mucus. Sperm motility parameters were not affected by the addition of nicotine to semen samples incubated with BWW medium. Overall, these results suggest that a direct inhibitory effect of nicotine on sperm penetrability through cervical mucus is not responsible for the apparent increase in cervical factor infertility present in smoking women.

Original languageEnglish (US)
Pages (from-to)722-724
Number of pages3
JournalFertility and Sterility
Volume51
Issue number4
DOIs
StatePublished - Jan 1 1989

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