Abstract
The effect of ions on enzyme activity and stability usually follows the Hofmeister series (or the kosmotropicity order): kosmotropic anions and chaotropic cations stabilize enzymes while chaotropic anions and kosmotropic cations destabilize them. The effect of ionic liquids (ILs) on the enzyme activity/stability/enantioselectivity is complicated especially when there is no or little water presence in the IL media. However, when aqueous solutions of hydrophilic ILs are employed as reaction media, the enzyme seems to follow the Hofmeister series since ILs dissociate into individual ions in water.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 16-25 |
| Number of pages | 10 |
| Journal | Journal of Molecular Catalysis B: Enzymatic |
| Volume | 37 |
| Issue number | 1-6 |
| DOIs | |
| State | Published - Dec 1 2005 |
| Externally published | Yes |
Bibliographical note
Funding Information:This project was supported by the NIH EARDA grant (No. 5 G11 HD 32861-08) and the 2005 NSF MAGEC-STEM Summer Research Program. The author is also very grateful for constructive suggestions from the anonymous reviewer.
Keywords
- Activity
- Enzyme
- Hofmeister series
- Ion
- Ionic liquid
- Stability
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