TY - JOUR
T1 - Effect of homatropine eye drops on pain after photorefractive keratectomy
T2 - A pilot study
AU - Joshaghani, Mahmoud
AU - Nazari, Hossein
AU - Ghasemi Falavarjani, Khalil
AU - Shokrollahi, Siamak
AU - Jafar Ghaempanah, Mohammad
AU - Abri Aghdam, Kaveh
AU - Mirbolouk Jalali, Zahra
PY - 2013/4
Y1 - 2013/4
N2 - Purpose: To assess the effect of homatropine eye drops on pain after photorefractive keratectomy (PRK). Methods: This randomized, double masked, interventional study included 15 patients (30 eyes) who underwent bilateral PRK. After operation, patients received homatropine eye drops, 4 times daily in only one eye (homatropine eye). The level of pain was evaluated using visual analogue scale (VAS), verbal rating scale (VRS) and pain rating index (PRI) at 0.5, 24 and 48. h after operation. Results: The level of pain was statistically similar between the two eyes half an hour after operation, however, homatropine eyes had significantly less pain 24. h after operation compared to fellow eyes (2.5 ± 1.9 vs 5.3 ± 2.5, P = 0.004 for VAS, 2.0. ± 1.2 vs 3.2 ± 0.9, P = 0.023 for VRS, and 9.4 ± 5.7 vs 16.0 ± 9.0, P = 0.031 for PRI). Also, 48. h after surgery, the pain scales were less in the homatropine eyes (2.3 ± 1.7 vs 4.0 ± 2.1, P = 0.014 for VAS, 1.6 ± 1.0 vs 2.5 ± 1.0, P = 0.038 for VRS, and 6.8 ± 5.7 vs 12.0 ± 8.9, P = 0.005 for PRI). No delayed epithelial healing was observed. Conclusion: Homatropine eye drops may be useful for reducing pain after Photorefractive keratectomy.
AB - Purpose: To assess the effect of homatropine eye drops on pain after photorefractive keratectomy (PRK). Methods: This randomized, double masked, interventional study included 15 patients (30 eyes) who underwent bilateral PRK. After operation, patients received homatropine eye drops, 4 times daily in only one eye (homatropine eye). The level of pain was evaluated using visual analogue scale (VAS), verbal rating scale (VRS) and pain rating index (PRI) at 0.5, 24 and 48. h after operation. Results: The level of pain was statistically similar between the two eyes half an hour after operation, however, homatropine eyes had significantly less pain 24. h after operation compared to fellow eyes (2.5 ± 1.9 vs 5.3 ± 2.5, P = 0.004 for VAS, 2.0. ± 1.2 vs 3.2 ± 0.9, P = 0.023 for VRS, and 9.4 ± 5.7 vs 16.0 ± 9.0, P = 0.031 for PRI). Also, 48. h after surgery, the pain scales were less in the homatropine eyes (2.3 ± 1.7 vs 4.0 ± 2.1, P = 0.014 for VAS, 1.6 ± 1.0 vs 2.5 ± 1.0, P = 0.038 for VRS, and 6.8 ± 5.7 vs 12.0 ± 8.9, P = 0.005 for PRI). No delayed epithelial healing was observed. Conclusion: Homatropine eye drops may be useful for reducing pain after Photorefractive keratectomy.
KW - Mydriatics
KW - Pain
KW - Photorefractive keratectomy
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U2 - 10.1016/j.sjopt.2012.07.003
DO - 10.1016/j.sjopt.2012.07.003
M3 - Article
AN - SCOPUS:84878653778
SN - 1319-4534
VL - 27
SP - 83
EP - 85
JO - Saudi Journal of Ophthalmology
JF - Saudi Journal of Ophthalmology
IS - 2
ER -