Abstract
Transforming Ha-ras enhances the mitogen-induced activation of both the Ca2+-influx and the furosemide-sensitive Na+/K+/2Cl--cotransporter. Both systems represent essential early steps of mitogenic signal transduction in NIH 3T3 fibroblasts.
Original language | English (US) |
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Pages (from-to) | 163-176 |
Number of pages | 14 |
Journal | Advances in Enzyme Regulation |
Volume | 32 |
Issue number | C |
DOIs | |
State | Published - 1992 |
Externally published | Yes |
Bibliographical note
Funding Information:The excellent technical assistance by G. Bunde and E. Kindler is gratefully acknowledged. These studies were supported in part by a grant from the Federal Ministry of Research and Technology of the Federal Republic of Germany as part of the program "Cell biological and biotechnological procedures for the development of anti-tumor agents". These studies were also supported in part by a grant from "D. Swarovski-Leopold-Franzens-Universit/it, Innsbruck F6rderungsfonds".