Effect of cytokines on anticryptococcal activity of human microglial cells

Myriam M. Lipovsky, Amadu E. Juliana, Genya Gekker, Shuxian Hu, Andy I M Hoepelman, Phillip K. Peterson

Research output: Contribution to journalShort surveypeer-review

15 Scopus citations

Abstract

The effect of selected cytokines on the antifungal activity of human microglia was studied with encapsulated and acapsular strains of Cryptococcus neoformans. None of the cytokines tested increased the fungistatic activity of microglia, suggesting that killing of cryptococci within the central nervous system is dependent on other host defense mechanisms.

Original languageEnglish (US)
Pages (from-to)410-411
Number of pages2
JournalClinical and Diagnostic Laboratory Immunology
Volume5
Issue number3
DOIs
StatePublished - 1998

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