Effect of cytokines on anticryptococcal activity of human microglial cells

Myriam M. Lipovsky; Amadu E. Juliana; Genya Gekker; Shuxian Hu; Andy I M Hoepelman; Phillip K. Peterson

doi:10.1128/cdli.5.3.410-411.1998

Effect of cytokines on anticryptococcal activity of human microglial cells

Myriam M. Lipovsky, Amadu E. Juliana, Genya Gekker, Shuxian Hu, Andy I M Hoepelman, Phillip K. Peterson

Research output: Contribution to journal › Short survey › peer-review

18 Scopus citations

Abstract

The effect of selected cytokines on the antifungal activity of human microglia was studied with encapsulated and acapsular strains of Cryptococcus neoformans. None of the cytokines tested increased the fungistatic activity of microglia, suggesting that killing of cryptococci within the central nervous system is dependent on other host defense mechanisms.

Original language	English (US)
Pages (from-to)	410-411
Number of pages	2
Journal	Clinical and Diagnostic Laboratory Immunology
Volume	5
Issue number	3
DOIs	https://doi.org/10.1128/cdli.5.3.410-411.1998
State	Published - 1998

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title = "Effect of cytokines on anticryptococcal activity of human microglial cells",

abstract = "The effect of selected cytokines on the antifungal activity of human microglia was studied with encapsulated and acapsular strains of Cryptococcus neoformans. None of the cytokines tested increased the fungistatic activity of microglia, suggesting that killing of cryptococci within the central nervous system is dependent on other host defense mechanisms.",

author = "Lipovsky, {Myriam M.} and Juliana, {Amadu E.} and Genya Gekker and Shuxian Hu and Hoepelman, {Andy I M} and Peterson, {Phillip K.}",

year = "1998",

doi = "10.1128/cdli.5.3.410-411.1998",

language = "English (US)",

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pages = "410--411",

journal = "Clinical and Diagnostic Laboratory Immunology",

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publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Effect of cytokines on anticryptococcal activity of human microglial cells

AU - Lipovsky, Myriam M.

AU - Juliana, Amadu E.

AU - Gekker, Genya

AU - Hu, Shuxian

AU - Hoepelman, Andy I M

AU - Peterson, Phillip K.

PY - 1998

Y1 - 1998

N2 - The effect of selected cytokines on the antifungal activity of human microglia was studied with encapsulated and acapsular strains of Cryptococcus neoformans. None of the cytokines tested increased the fungistatic activity of microglia, suggesting that killing of cryptococci within the central nervous system is dependent on other host defense mechanisms.

AB - The effect of selected cytokines on the antifungal activity of human microglia was studied with encapsulated and acapsular strains of Cryptococcus neoformans. None of the cytokines tested increased the fungistatic activity of microglia, suggesting that killing of cryptococci within the central nervous system is dependent on other host defense mechanisms.

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U2 - 10.1128/cdli.5.3.410-411.1998

DO - 10.1128/cdli.5.3.410-411.1998

M3 - Short survey

C2 - 9606001

AN - SCOPUS:0031803676

SN - 1071-412X

VL - 5

SP - 410

EP - 411

JO - Clinical and Diagnostic Laboratory Immunology

JF - Clinical and Diagnostic Laboratory Immunology

IS - 3

ER -

Effect of cytokines on anticryptococcal activity of human microglial cells

Abstract

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