TY - JOUR
T1 - Effect of Curcuma longa freeze dried rhizome powder with milk in STZ induced diabetic rats
AU - Rai, P. K.
AU - Jaiswal, D.
AU - Mehta, S.
AU - Rai, D. K.
AU - Sharma, B.
AU - Watal, Geeta
PY - 2010/4
Y1 - 2010/4
N2 - This study deals with the effects of freeze dried rhizome powder of Curcuma longa (C. longa) dissolved in milk on normal as well as diabetic models. Diabetes of type II and type I was within 3 days of a single administration of doses of 45 and 65 mg kg-1 of streptozotocin respectively. Various parameters such as blood glucose levels, triglycerides, total cholesterol, high density lipoprotein, very low density lipoprotein, low density lipoprotein, serum glutamic oxaloacetic transaminase, serum glutamic pyruvate transaminase, alkaline phosphatase, creatinine, hemoglobin, urine protein and urine sugar in addition to body weight were taken in to consideration and were analyzed after administration of variable doses of rhizome powder. The dose of 200 mg kg -1 was identified as the most effective dose as it increased HDL, Hb and bw (P<0.05) with significant decrease in the levels of blood glucose, lipid profile and hepatoprotective enzymes (P<0.001).
AB - This study deals with the effects of freeze dried rhizome powder of Curcuma longa (C. longa) dissolved in milk on normal as well as diabetic models. Diabetes of type II and type I was within 3 days of a single administration of doses of 45 and 65 mg kg-1 of streptozotocin respectively. Various parameters such as blood glucose levels, triglycerides, total cholesterol, high density lipoprotein, very low density lipoprotein, low density lipoprotein, serum glutamic oxaloacetic transaminase, serum glutamic pyruvate transaminase, alkaline phosphatase, creatinine, hemoglobin, urine protein and urine sugar in addition to body weight were taken in to consideration and were analyzed after administration of variable doses of rhizome powder. The dose of 200 mg kg -1 was identified as the most effective dose as it increased HDL, Hb and bw (P<0.05) with significant decrease in the levels of blood glucose, lipid profile and hepatoprotective enzymes (P<0.001).
KW - Antidiabetic
KW - Curcuma longa rhizome
KW - Freeze dried
KW - Hepatoprotective
KW - Hypolipidemic
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U2 - 10.1007/s12291-010-0032-z
DO - 10.1007/s12291-010-0032-z
M3 - Article
C2 - 23105906
AN - SCOPUS:77955453016
SN - 0970-1915
VL - 25
SP - 175
EP - 181
JO - Indian Journal of Clinical Biochemistry
JF - Indian Journal of Clinical Biochemistry
IS - 2
ER -