Effect of coronary angioplasty on QT dispersion

R. F. Kelly, J. E. Parillo, S. M. Hollenberg

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Increased QT dispersion (QT(max) - QT(min) [QTd]) reflects inhomogeneous ventricular repolarization that may provide a substrate for serious arrhythmias and is associated with adverse clinical outcomes in patients with heart disease. Effective treatment of acute myocardial infarction or ventricular arrhythmias may reduce QTd, but the effect of coronary revascularization on QTd in patients without these conditions is unknown. In this study, QTd was measured before and 4 and 24 hours after successful angioplasty in 94 patients without ongoing symptomatic myocardial ischemia or malignant arrhythmias. QTd decreased from 434 ± 17 msec before angioplasty to 354 ±15 msec 4 hours (p < 0.05) and 33 ± 14 msec 24 hours after angioplasty (p < 0.05). QTd was improved in 64% of patients, worse in 28%, and unchanged in 8%. Thus angioplasty significantly improves QTd. This may reflect increased myocardial perfusion and may be inherently beneficial by reducing the propensity for arrhythmias.

Original languageEnglish (US)
Pages (from-to)399-405
Number of pages7
JournalAmerican Heart Journal
Volume134
Issue number3
DOIs
StatePublished - Jan 1 1997

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