Effect of centrally administered corticotropin releasing factor (CRF) on multiple feeding paradigms

A. S. Levine, Bernetta Rogers, Julie Kneip, Martha Grace, J. E. Morley

Research output: Contribution to journalArticlepeer-review

122 Scopus citations

Abstract

Recently, a 41-residue corticotropin-releasing factor (CRF) has been characterized from the hypothalamus. In the present study, it was found that this stress-related peptide suppressed feeding induced by a variety of substances including muscimol, norepinephrine, dynorphin and insulin. These data suggest that the corticotropin-releasing factor may represent an important agent in stress-induced anorexia.

Original languageEnglish (US)
Pages (from-to)337-339
Number of pages3
JournalNeuropharmacology
Volume22
Issue number3 PART 1
DOIs
StatePublished - Mar 1983

Keywords

  • CRF
  • anorexia
  • dynorphin
  • feeding
  • insulin
  • muscimol
  • norepinephrine
  • stress

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