Multimodal neuroimaging, such as combined electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), are being increasingly used to investigate the human brain in healthy and diseased conditions. However, certain neuroimaging data are typically acquired in different body positions, e.g., supine fMRI and upright EEG, overlooking the effect of body position on signal characteristics. In the current study we examined EEG signals in three different positions, i.e., supine, standing and sitting, in patients with a balance disorder called mal de debarquement syndrome (MdDS). Individuals with MdDS experience a chronic illusion of self-motion triggered by prolonged exposure to passive motion, such as from sea or air travel. The degree of perception of rocking dizziness is modulated by body position, suggesting a physiological effect related to body positions. In the present study, EEG features were quantified as peak frequency, peak amplitude, and average amplitude of the alpha band due to its strongest signal characteristics compared to other frequencies. The effect of body position was examined in EEG features from data acquired before and after the individuals received treatment with repetitive transcranial magnetic stimulation. Our results indicate a significant effect of body positions on the EEG signals in MdDS.
|Original language||English (US)|
|Title of host publication||40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018|
|Publisher||Institute of Electrical and Electronics Engineers Inc.|
|Number of pages||4|
|State||Published - Oct 26 2018|
|Event||40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 - Honolulu, United States|
Duration: Jul 18 2018 → Jul 21 2018
|Name||Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS|
|Other||40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018|
|Period||7/18/18 → 7/21/18|
Bibliographical noteFunding Information:
*This work was supported in part by NSF RII Track-2 FEC 1539068, NIH/NIDCD R03 DC010451, an equipment grant from the MdDS Balance Disorders Foundation and NIH/NIGMS P20 GM121312.