Effect of 10.5 M Aqueous Urea on Helicobacter pylori Urease: A Molecular Dynamics Study

Keyphrases

• Urea 100%
• Active Sites 100%
• Molecular Dynamics Study 100%
• Aqueous Urea Solution 100%
• Helicobacter Pylori Urease 100%
• Flap 80%
• Simulation Time 40%
• Highest Root 40%
• Root Mean Square Fluctuation 40%
• Molecular Dynamics Simulation 20%
• Helicobacter Pylori (H. pylori) 20%
• Water Molecule 20%
• Solvate 20%
• Extended Period 20%
• Millisecond Interval 20%
• Denaturation 20%
• Ingress 20%
• Solvent Accessible Surface Area 20%
• Specific Pattern 20%
• Denaturants 20%
• Pentacoordinate 20%
• Urease 20%
• Klebsiella 20%
• Ni2+ 20%
• Protein Secondary Structure 20%
• Adapted M-solutions 20%
• Hydrolysis Mechanism 20%
• Urea Denaturation 20%
• Urea Solution 20%
• Unique Pattern 20%

Biochemistry, Genetics and Molecular Biology

• Active Site 100%
• Dynamics 100%
• Helicobacter Pylori 100%
• Urease 100%
• Solution and Solubility 60%
• Denaturation 40%
• Enzymatic Hydrolysis 20%
• Protein Secondary Structure 20%
• Enzyme 20%
• Accessible Surface Area 20%
• Klebsiella 20%
• Computer Simulation 20%