Early use of the vacuum constriction device following radical retropubic prostatectomy

A randomized clinical trial

Manoj Monga, Tobias Kohler, Kari Hendlin, Igor Ryndin, Benjamin K. Canales, Derek Weiland, Nissrine A Nakib, Anup P. Ramani, Kyle Anderson, Pratap Reddy, Roland R Ugarte

Research output: Contribution to conferenceAbstract

Abstract

Objectives: Erectile dysfunction (ED) and penile shortening after radical retropubic prostatectomy (RRP) are important concerns for men considering treatment alternatives for localized prostate cancer. We evaluated the impact of early utilization of the vacuum constriction device (VCD) on these outcomes.

Methods: Thirty-five patients undergoing radical retropubic prostatectomy were randomized to early (1 month post-operative, EARLY) or traditional (6 months postoperative, TRAD) use of the VCD. Preoperative International Index of Erectile Function of +/-11 (IIEF; no ED or mild ED) were required as a baseline inclusion criterion. EARLY subjects followed a daily rehabilitation protocol consisting of 10 minutes/day without the constriction ring for 5 months. Subjects were evaluated with the IIEF and measurements of the stretched penile length, a surrogate for erect penile length, preoperatively and at 1, 3, 6, 9 and 12 months.

Results: Bilateral nerve sparing was accomplished in 26 patients. IIEF scores were significantly higher in the EARLY Group than the TRAD Group at 3 months (13.99.0 vs. 2.4 +/- 1.7, p=0.002) and 6 months (12.0 +/- 8.8 vs. 2.8 +/- 2.0, p=0.029) postoperative. Fewer patients in the EARLY Group suffered from moderate to severe ED (IIEF=11) at 3 months (60% vs. 100%, p=0.002) and 6 months (50% vs. 100%, p=0.03). Significant shortening of the stretched penile length (1cm) was seen in 27% of the EARLY Group compared to 64% in the TRAD Group (p=0.06) at last follow-up.

Conclusions: Early initiation of use of the vacuum constriction device at 1-month post-radical prostatectomy improves early sexual functioning and may help preserve penile length.
Original languageEnglish (US)
Pages262
StatePublished - Nov 2006

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Erectile Dysfunction
Prostatectomy
Vacuum
Constriction
Randomized Controlled Trials
Equipment and Supplies
Prostatic Neoplasms
Rehabilitation
Therapeutics

Cite this

Monga, M., Kohler, T., Hendlin, K., Ryndin, I., Canales, B. K., Weiland, D., ... Ugarte, R. R. (2006). Early use of the vacuum constriction device following radical retropubic prostatectomy: A randomized clinical trial. 262.

Early use of the vacuum constriction device following radical retropubic prostatectomy : A randomized clinical trial. / Monga, Manoj; Kohler, Tobias; Hendlin, Kari; Ryndin, Igor; Canales, Benjamin K.; Weiland, Derek; Nakib, Nissrine A; Ramani, Anup P.; Anderson, Kyle; Reddy, Pratap; Ugarte, Roland R.

2006. 262.

Research output: Contribution to conferenceAbstract

Monga, M, Kohler, T, Hendlin, K, Ryndin, I, Canales, BK, Weiland, D, Nakib, NA, Ramani, AP, Anderson, K, Reddy, P & Ugarte, RR 2006, 'Early use of the vacuum constriction device following radical retropubic prostatectomy: A randomized clinical trial' pp. 262.
Monga, Manoj ; Kohler, Tobias ; Hendlin, Kari ; Ryndin, Igor ; Canales, Benjamin K. ; Weiland, Derek ; Nakib, Nissrine A ; Ramani, Anup P. ; Anderson, Kyle ; Reddy, Pratap ; Ugarte, Roland R. / Early use of the vacuum constriction device following radical retropubic prostatectomy : A randomized clinical trial.
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title = "Early use of the vacuum constriction device following radical retropubic prostatectomy: A randomized clinical trial",
abstract = "Objectives: Erectile dysfunction (ED) and penile shortening after radical retropubic prostatectomy (RRP) are important concerns for men considering treatment alternatives for localized prostate cancer. We evaluated the impact of early utilization of the vacuum constriction device (VCD) on these outcomes.Methods: Thirty-five patients undergoing radical retropubic prostatectomy were randomized to early (1 month post-operative, EARLY) or traditional (6 months postoperative, TRAD) use of the VCD. Preoperative International Index of Erectile Function of +/-11 (IIEF; no ED or mild ED) were required as a baseline inclusion criterion. EARLY subjects followed a daily rehabilitation protocol consisting of 10 minutes/day without the constriction ring for 5 months. Subjects were evaluated with the IIEF and measurements of the stretched penile length, a surrogate for erect penile length, preoperatively and at 1, 3, 6, 9 and 12 months.Results: Bilateral nerve sparing was accomplished in 26 patients. IIEF scores were significantly higher in the EARLY Group than the TRAD Group at 3 months (13.99.0 vs. 2.4 +/- 1.7, p=0.002) and 6 months (12.0 +/- 8.8 vs. 2.8 +/- 2.0, p=0.029) postoperative. Fewer patients in the EARLY Group suffered from moderate to severe ED (IIEF=11) at 3 months (60{\%} vs. 100{\%}, p=0.002) and 6 months (50{\%} vs. 100{\%}, p=0.03). Significant shortening of the stretched penile length (1cm) was seen in 27{\%} of the EARLY Group compared to 64{\%} in the TRAD Group (p=0.06) at last follow-up.Conclusions: Early initiation of use of the vacuum constriction device at 1-month post-radical prostatectomy improves early sexual functioning and may help preserve penile length.",
author = "Manoj Monga and Tobias Kohler and Kari Hendlin and Igor Ryndin and Canales, {Benjamin K.} and Derek Weiland and Nakib, {Nissrine A} and Ramani, {Anup P.} and Kyle Anderson and Pratap Reddy and Ugarte, {Roland R}",
year = "2006",
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language = "English (US)",
pages = "262",

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TY - CONF

T1 - Early use of the vacuum constriction device following radical retropubic prostatectomy

T2 - A randomized clinical trial

AU - Monga, Manoj

AU - Kohler, Tobias

AU - Hendlin, Kari

AU - Ryndin, Igor

AU - Canales, Benjamin K.

AU - Weiland, Derek

AU - Nakib, Nissrine A

AU - Ramani, Anup P.

AU - Anderson, Kyle

AU - Reddy, Pratap

AU - Ugarte, Roland R

PY - 2006/11

Y1 - 2006/11

N2 - Objectives: Erectile dysfunction (ED) and penile shortening after radical retropubic prostatectomy (RRP) are important concerns for men considering treatment alternatives for localized prostate cancer. We evaluated the impact of early utilization of the vacuum constriction device (VCD) on these outcomes.Methods: Thirty-five patients undergoing radical retropubic prostatectomy were randomized to early (1 month post-operative, EARLY) or traditional (6 months postoperative, TRAD) use of the VCD. Preoperative International Index of Erectile Function of +/-11 (IIEF; no ED or mild ED) were required as a baseline inclusion criterion. EARLY subjects followed a daily rehabilitation protocol consisting of 10 minutes/day without the constriction ring for 5 months. Subjects were evaluated with the IIEF and measurements of the stretched penile length, a surrogate for erect penile length, preoperatively and at 1, 3, 6, 9 and 12 months.Results: Bilateral nerve sparing was accomplished in 26 patients. IIEF scores were significantly higher in the EARLY Group than the TRAD Group at 3 months (13.99.0 vs. 2.4 +/- 1.7, p=0.002) and 6 months (12.0 +/- 8.8 vs. 2.8 +/- 2.0, p=0.029) postoperative. Fewer patients in the EARLY Group suffered from moderate to severe ED (IIEF=11) at 3 months (60% vs. 100%, p=0.002) and 6 months (50% vs. 100%, p=0.03). Significant shortening of the stretched penile length (1cm) was seen in 27% of the EARLY Group compared to 64% in the TRAD Group (p=0.06) at last follow-up.Conclusions: Early initiation of use of the vacuum constriction device at 1-month post-radical prostatectomy improves early sexual functioning and may help preserve penile length.

AB - Objectives: Erectile dysfunction (ED) and penile shortening after radical retropubic prostatectomy (RRP) are important concerns for men considering treatment alternatives for localized prostate cancer. We evaluated the impact of early utilization of the vacuum constriction device (VCD) on these outcomes.Methods: Thirty-five patients undergoing radical retropubic prostatectomy were randomized to early (1 month post-operative, EARLY) or traditional (6 months postoperative, TRAD) use of the VCD. Preoperative International Index of Erectile Function of +/-11 (IIEF; no ED or mild ED) were required as a baseline inclusion criterion. EARLY subjects followed a daily rehabilitation protocol consisting of 10 minutes/day without the constriction ring for 5 months. Subjects were evaluated with the IIEF and measurements of the stretched penile length, a surrogate for erect penile length, preoperatively and at 1, 3, 6, 9 and 12 months.Results: Bilateral nerve sparing was accomplished in 26 patients. IIEF scores were significantly higher in the EARLY Group than the TRAD Group at 3 months (13.99.0 vs. 2.4 +/- 1.7, p=0.002) and 6 months (12.0 +/- 8.8 vs. 2.8 +/- 2.0, p=0.029) postoperative. Fewer patients in the EARLY Group suffered from moderate to severe ED (IIEF=11) at 3 months (60% vs. 100%, p=0.002) and 6 months (50% vs. 100%, p=0.03). Significant shortening of the stretched penile length (1cm) was seen in 27% of the EARLY Group compared to 64% in the TRAD Group (p=0.06) at last follow-up.Conclusions: Early initiation of use of the vacuum constriction device at 1-month post-radical prostatectomy improves early sexual functioning and may help preserve penile length.

M3 - Abstract

SP - 262

ER -