Early motor abilities in infants at heightened versus low risk for ASD: A Baby Siblings Research Consortium (BSRC) study

Jana M. Iverson, Frederick Shic, Carla A. Wall, Katarzyna Chawarska, Suzanne Curtin, Annette Estes, Judith M. Gardner, Ted Hutman, Rebecca J. Landa, April R. Levin, Klaus Libertus, Daniel S. Messinger, Charles A. Nelson, Sally Ozonoff, Lori Ann R. Sacrey, Kelly Sheperd, Wendy L. Stone, Helen B. Tager-Flusberg, Jason J. Wolff, Nurit YirmiyaGregory S. Young

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Research has identified early appearing differences in gross and fine motor abilities in infants at heightened risk (HR) for autism spectrum disorder (ASD) because they are the younger siblings of children with ASD, and it suggests that such differences may be especially apparent among those HR infants themselves eventually diagnosed with ASD. The present study examined overall and item-level performance on the gross (GM) and fine motor (FM) subscales of the Mullen Scales of Early Learning (MSEL) administered at 6 months to a large, geographically diverse sample of HR infants with varying developmental outcomes (ASD, elevated ADOS without ASD, low ADOS without ASD) and to infants with low ASD risk (low risk [LR]). We also explored whether motor abilities assessed at 6 months predicted ASD symptom severity at 36 months. FM (but not GM) performance distinguished all 3 HR groups from LR infants with the weakest performance observed in the HR-Elevated ADOS children, who exhibited multiple differences from both LR and other HR infants in both gross and fine motor skills. Finally, 6-month FM (but not GM) scores significant predicted 36-month ADOS severity scores in the HR group; but no evidence was found of specific early appearing motor signs associated with a later ASD diagnosis. Vulnerabilities in infants' fine and gross motor skills may have significant consequences for later development not only in the motor domain but in other domains.

Original languageEnglish (US)
Pages (from-to)69-80
Number of pages12
JournalJournal of abnormal psychology
Volume128
Issue number1
DOIs
StatePublished - Jan 2019

Fingerprint

Aptitude
Siblings
Research
Motor Skills
Autism Spectrum Disorder
Learning

Keywords

  • ASD
  • early identification
  • fine motor
  • gross motor
  • infant siblings

Cite this

Early motor abilities in infants at heightened versus low risk for ASD : A Baby Siblings Research Consortium (BSRC) study. / Iverson, Jana M.; Shic, Frederick; Wall, Carla A.; Chawarska, Katarzyna; Curtin, Suzanne; Estes, Annette; Gardner, Judith M.; Hutman, Ted; Landa, Rebecca J.; Levin, April R.; Libertus, Klaus; Messinger, Daniel S.; Nelson, Charles A.; Ozonoff, Sally; Sacrey, Lori Ann R.; Sheperd, Kelly; Stone, Wendy L.; Tager-Flusberg, Helen B.; Wolff, Jason J.; Yirmiya, Nurit; Young, Gregory S.

In: Journal of abnormal psychology, Vol. 128, No. 1, 01.2019, p. 69-80.

Research output: Contribution to journalArticle

Iverson, JM, Shic, F, Wall, CA, Chawarska, K, Curtin, S, Estes, A, Gardner, JM, Hutman, T, Landa, RJ, Levin, AR, Libertus, K, Messinger, DS, Nelson, CA, Ozonoff, S, Sacrey, LAR, Sheperd, K, Stone, WL, Tager-Flusberg, HB, Wolff, JJ, Yirmiya, N & Young, GS 2019, 'Early motor abilities in infants at heightened versus low risk for ASD: A Baby Siblings Research Consortium (BSRC) study', Journal of abnormal psychology, vol. 128, no. 1, pp. 69-80. https://doi.org/10.1037/abn0000390
Iverson, Jana M. ; Shic, Frederick ; Wall, Carla A. ; Chawarska, Katarzyna ; Curtin, Suzanne ; Estes, Annette ; Gardner, Judith M. ; Hutman, Ted ; Landa, Rebecca J. ; Levin, April R. ; Libertus, Klaus ; Messinger, Daniel S. ; Nelson, Charles A. ; Ozonoff, Sally ; Sacrey, Lori Ann R. ; Sheperd, Kelly ; Stone, Wendy L. ; Tager-Flusberg, Helen B. ; Wolff, Jason J. ; Yirmiya, Nurit ; Young, Gregory S. / Early motor abilities in infants at heightened versus low risk for ASD : A Baby Siblings Research Consortium (BSRC) study. In: Journal of abnormal psychology. 2019 ; Vol. 128, No. 1. pp. 69-80.
@article{d3d84dbedffe427e94ab138316714455,
title = "Early motor abilities in infants at heightened versus low risk for ASD: A Baby Siblings Research Consortium (BSRC) study",
abstract = "Research has identified early appearing differences in gross and fine motor abilities in infants at heightened risk (HR) for autism spectrum disorder (ASD) because they are the younger siblings of children with ASD, and it suggests that such differences may be especially apparent among those HR infants themselves eventually diagnosed with ASD. The present study examined overall and item-level performance on the gross (GM) and fine motor (FM) subscales of the Mullen Scales of Early Learning (MSEL) administered at 6 months to a large, geographically diverse sample of HR infants with varying developmental outcomes (ASD, elevated ADOS without ASD, low ADOS without ASD) and to infants with low ASD risk (low risk [LR]). We also explored whether motor abilities assessed at 6 months predicted ASD symptom severity at 36 months. FM (but not GM) performance distinguished all 3 HR groups from LR infants with the weakest performance observed in the HR-Elevated ADOS children, who exhibited multiple differences from both LR and other HR infants in both gross and fine motor skills. Finally, 6-month FM (but not GM) scores significant predicted 36-month ADOS severity scores in the HR group; but no evidence was found of specific early appearing motor signs associated with a later ASD diagnosis. Vulnerabilities in infants' fine and gross motor skills may have significant consequences for later development not only in the motor domain but in other domains.",
keywords = "ASD, early identification, fine motor, gross motor, infant siblings",
author = "Iverson, {Jana M.} and Frederick Shic and Wall, {Carla A.} and Katarzyna Chawarska and Suzanne Curtin and Annette Estes and Gardner, {Judith M.} and Ted Hutman and Landa, {Rebecca J.} and Levin, {April R.} and Klaus Libertus and Messinger, {Daniel S.} and Nelson, {Charles A.} and Sally Ozonoff and Sacrey, {Lori Ann R.} and Kelly Sheperd and Stone, {Wendy L.} and Tager-Flusberg, {Helen B.} and Wolff, {Jason J.} and Nurit Yirmiya and Young, {Gregory S.}",
year = "2019",
month = "1",
doi = "10.1037/abn0000390",
language = "English (US)",
volume = "128",
pages = "69--80",
journal = "Journal of Abnormal Psychology",
issn = "0021-843X",
publisher = "American Psychological Association",
number = "1",

}

TY - JOUR

T1 - Early motor abilities in infants at heightened versus low risk for ASD

T2 - A Baby Siblings Research Consortium (BSRC) study

AU - Iverson, Jana M.

AU - Shic, Frederick

AU - Wall, Carla A.

AU - Chawarska, Katarzyna

AU - Curtin, Suzanne

AU - Estes, Annette

AU - Gardner, Judith M.

AU - Hutman, Ted

AU - Landa, Rebecca J.

AU - Levin, April R.

AU - Libertus, Klaus

AU - Messinger, Daniel S.

AU - Nelson, Charles A.

AU - Ozonoff, Sally

AU - Sacrey, Lori Ann R.

AU - Sheperd, Kelly

AU - Stone, Wendy L.

AU - Tager-Flusberg, Helen B.

AU - Wolff, Jason J.

AU - Yirmiya, Nurit

AU - Young, Gregory S.

PY - 2019/1

Y1 - 2019/1

N2 - Research has identified early appearing differences in gross and fine motor abilities in infants at heightened risk (HR) for autism spectrum disorder (ASD) because they are the younger siblings of children with ASD, and it suggests that such differences may be especially apparent among those HR infants themselves eventually diagnosed with ASD. The present study examined overall and item-level performance on the gross (GM) and fine motor (FM) subscales of the Mullen Scales of Early Learning (MSEL) administered at 6 months to a large, geographically diverse sample of HR infants with varying developmental outcomes (ASD, elevated ADOS without ASD, low ADOS without ASD) and to infants with low ASD risk (low risk [LR]). We also explored whether motor abilities assessed at 6 months predicted ASD symptom severity at 36 months. FM (but not GM) performance distinguished all 3 HR groups from LR infants with the weakest performance observed in the HR-Elevated ADOS children, who exhibited multiple differences from both LR and other HR infants in both gross and fine motor skills. Finally, 6-month FM (but not GM) scores significant predicted 36-month ADOS severity scores in the HR group; but no evidence was found of specific early appearing motor signs associated with a later ASD diagnosis. Vulnerabilities in infants' fine and gross motor skills may have significant consequences for later development not only in the motor domain but in other domains.

AB - Research has identified early appearing differences in gross and fine motor abilities in infants at heightened risk (HR) for autism spectrum disorder (ASD) because they are the younger siblings of children with ASD, and it suggests that such differences may be especially apparent among those HR infants themselves eventually diagnosed with ASD. The present study examined overall and item-level performance on the gross (GM) and fine motor (FM) subscales of the Mullen Scales of Early Learning (MSEL) administered at 6 months to a large, geographically diverse sample of HR infants with varying developmental outcomes (ASD, elevated ADOS without ASD, low ADOS without ASD) and to infants with low ASD risk (low risk [LR]). We also explored whether motor abilities assessed at 6 months predicted ASD symptom severity at 36 months. FM (but not GM) performance distinguished all 3 HR groups from LR infants with the weakest performance observed in the HR-Elevated ADOS children, who exhibited multiple differences from both LR and other HR infants in both gross and fine motor skills. Finally, 6-month FM (but not GM) scores significant predicted 36-month ADOS severity scores in the HR group; but no evidence was found of specific early appearing motor signs associated with a later ASD diagnosis. Vulnerabilities in infants' fine and gross motor skills may have significant consequences for later development not only in the motor domain but in other domains.

KW - ASD

KW - early identification

KW - fine motor

KW - gross motor

KW - infant siblings

UR - http://www.scopus.com/inward/record.url?scp=85059795781&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85059795781&partnerID=8YFLogxK

U2 - 10.1037/abn0000390

DO - 10.1037/abn0000390

M3 - Article

C2 - 30628809

AN - SCOPUS:85059795781

VL - 128

SP - 69

EP - 80

JO - Journal of Abnormal Psychology

JF - Journal of Abnormal Psychology

SN - 0021-843X

IS - 1

ER -