Early Imaging Associated With Improved Survival in Older Patients With Mild Traumatic Brain Injuries

Kristina Techar, Arthur Nguyen, Regina M. Lorenzo, Simon Yang, Brian Thielen, Anne Cain-Nielsen, Mark R. Hemmila, Christopher J Tignanelli

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background: Traumatic brain injury (TBI) is a leading cause of trauma-related death and disability. Computed tomography (CT) imaging of the head is essential for diagnosis of intracranial hemorrhage. This study aimed to identify optimal time to imaging and its impact on mortality for older patients with mild TBIs. Materials and methods: State-wide quality collaborative data were used from level I-II trauma centers. Inclusion criteria were ICD-9/10 codes for head trauma, age ≥50, admission/emergency department Glasgow Coma Scale ≥14, injury severity score ≤20, nonfull trauma activation, and head CT imaging time between 5 and 90 min of arrival. Locally weighted scatterplot smoothing plot data were used to dichotomize patients into early and late head CT imaging cohorts. Multivariable logistic regression and negative binomial models were used to evaluate the effect of early verses late head CT on clinical outcomes. The primary outcome was in-hospital mortality. Results: Mortality nadired at 35 min. Each 1-min delay in CT imaging resulted in a 2% increase in mortality (P = 0.002). Early patients had significantly reduced in-hospital mortality (P = 0.03), shorter emergency department length of stay (P < 0.001), and were more likely to receive fresh frozen plasma within 4 h if anticoagulated (P = 0.03). Teaching, high-volume, and level 2 trauma centers were all less likely to provide early head CTs (all P < 0.05). Conclusions: Delay in head CT imaging in the setting of potential mild TBI was associated with an increase in mortality. A delay in diagnosis cascades into delays in delivery of therapeutic interventions. Head CT within 35 min should be evaluated as a quality metric for older patients with mild TBI.

Original languageEnglish (US)
Pages (from-to)4-10
Number of pages7
JournalJournal of Surgical Research
Volume242
DOIs
StatePublished - Oct 2019

Bibliographical note

Funding Information:
M.R.H. and A.C-N. receive grant support from Blue Cross Blue Shield of Michigan and Blue Care Network (a nonprofit mutual company) for conduct of The Michigan Trauma Quality Improvement Program. For the remaining authors, no conflicts or disclosures were declared.

Publisher Copyright:
© 2019

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

Keywords

  • Head CT imaging
  • Quality improvement
  • Quality metrics
  • TBI
  • Trauma systems improvement

Fingerprint Dive into the research topics of 'Early Imaging Associated With Improved Survival in Older Patients With Mild Traumatic Brain Injuries'. Together they form a unique fingerprint.

Cite this