Dynorphin-(1-13) induces spontaneous feeding in rats

John E. Morley; Allen S. Levine

doi:10.1016/0024-3205(81)90522-1

Dynorphin-(1-13) induces spontaneous feeding in rats

John E. Morley, Allen S. Levine

Medicine - Administration

Research output: Contribution to journal › Article › peer-review

198 Scopus citations

Abstract

Dynorphin-(1-13), a recently isolated opioid peptide stimulates food ingestion in rats after intracerebroventricular administration at doses of 1 and 10 μg. The latency until food ingestion is 22.4 ± 1.9 min. The ability of dynorphin-(1-13) to initiate food ingestion is antagonized by the opiate antagonist, naloxone. The food ingestion is accompanied by excessive grooming behavior.

Original language	English (US)
Pages (from-to)	1901-1903
Number of pages	3
Journal	Life Sciences
Volume	29
Issue number	18
DOIs	https://doi.org/10.1016/0024-3205(81)90522-1
State	Published - Nov 2 1981

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title = "Dynorphin-(1-13) induces spontaneous feeding in rats",

abstract = "Dynorphin-(1-13), a recently isolated opioid peptide stimulates food ingestion in rats after intracerebroventricular administration at doses of 1 and 10 μg. The latency until food ingestion is 22.4 ± 1.9 min. The ability of dynorphin-(1-13) to initiate food ingestion is antagonized by the opiate antagonist, naloxone. The food ingestion is accompanied by excessive grooming behavior.",

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