We describe the dynamic manipulation of the charged lipids in a confined geometry where two dispersive factors arising from the random diffusion-based Brownian motion and the field-induced drift of target lipids compete with each other. It is found that the lateral distribution of the target lipids is well controlled through a combined effect of an external electric field and the geometric restrictions by the confinement. The dynamic manipulation scheme for the charged lipids in twodimension would be useful for understanding the spatial organization of membrane components in a supported lipid membrane mimicking a real cell membrane and for producing membrane-based microarrays.
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- Charged lipids
- Lateral distribution
- Supported lipid membrane