Dynamic manipulation of charged lipids in model membrane for bio-microarrays

Yong Sang Ryu, Jeng Hun Suh, Min Hoi Kim, Youngjoo Sohn, Sin Doo Lee

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We describe the dynamic manipulation of the charged lipids in a confined geometry where two dispersive factors arising from the random diffusion-based Brownian motion and the field-induced drift of target lipids compete with each other. It is found that the lateral distribution of the target lipids is well controlled through a combined effect of an external electric field and the geometric restrictions by the confinement. The dynamic manipulation scheme for the charged lipids in twodimension would be useful for understanding the spatial organization of membrane components in a supported lipid membrane mimicking a real cell membrane and for producing membrane-based microarrays.

Original languageEnglish (US)
Pages (from-to)6355-6359
Number of pages5
JournalJournal of Nanoscience and Nanotechnology
Volume16
Issue number6
DOIs
StatePublished - Jun 2016

Keywords

  • Bio-Microarray
  • Charged lipids
  • Lateral distribution
  • Supported lipid membrane

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