Substance abuse remains a serious medical, public health, and social problem. The impact on destructive public health and health costs compounded with the negative consequences of drugs abuse poses a significant toll on the economy. Despite significant advancement of research in the field treatment of and care of patients with substance abuse has lagged behind because of limited education and training of clinicians on substance abuse problems. The goal of the special issue is to provide the current status on the mechanisms underlying the increased prevalence of opportunistic infections in the drug abuse population, to identify important areas where further research would be beneficial and to open new avenues of investigation for therapeutic development. We aimed these articles for the benefit of both basic and clinical researchers.
Bibliographical noteFunding Information:
Acknowledgment I would like to express my profound gratitude to Dr. Howard E. Gendelman, Editor-in-Chief, for the opportunity to lead the special issue and his invaluable advice and guidance during the process. I would like to thank Ms. Robin Taylor for her assistance in preparing this special issue. This work was supported by National Institutes of Health grants NIH RO1 DA12104, RO1 DA022935, KO2 DA015349, R01 DA031202 and P50 DA11806 (S.R.). The author declares that she has no conflicts of interest.
- Acquired immunodeficiency syndrome
- Drugs of abuse
- Human immunodeficiency virus
- Immune disfunction
- Infectious diseases
- Innate and adaptive immunity
- Microbial pathogenesis
- Opportunistic infections
- Substance abuse