Drugs in use in the newborn: Effects on the kidney

T. M. Wahlig, T. R. Thompson, Alan R Sinaiko

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


In the neonate, there are a number of age-related differences in drug disposition (bioavailability, distribution, metabolism, and excretion), and these are directly related to the degree of prematurity. This article discusses the use of drugs that are commonly administered to the neonatal patient, with special emphasis given to renal considerations. These drugs include diuretics, theophylline, converting enzyme inhibitors, calcium channel blockers, indomethacin, and dopamine.

Original languageEnglish (US)
Pages (from-to)251-263
Number of pages13
JournalClinics in Perinatology
Issue number1
StatePublished - Jan 1 1992


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