Drug partnerships and global practices

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16 Scopus citations

Abstract

Tuberculosis poses one of the biggest threats to individuals living with HIV in most low-income regions of the world, and the increase of multi-drug resistant tuberculosis (MDR-TB) in South Africa, Eastern Europe, and elsewhere makes this threat that much more critical. Despite the extent of the problem, new drugs for tuberculosis have not been developed for over four decades, largely because tuberculosis occurs primarily among the poor in low-income regions and the market for tuberculosis drugs is not lucrative enough to warrant time and resource commitments by pharmaceutical companies. In the wake of sustained global criticism of pharmaceutical-state practices, however, new partnerships for drug development (PDPs) are forming to address critical shortages of drugs for diseases like tuberculosis that have been termed 'neglected' precisely because they have not seen new treatments for so long. This paper examines some of these partnerships, tracing some of the dynamic developments as well as challenges in forging alternative pathways to new drug and vaccine production.

Original languageEnglish (US)
Pages (from-to)481-489
Number of pages9
JournalHealth and Place
Volume18
Issue number3
DOIs
StatePublished - May 2012

Bibliographical note

Funding Information:
I would like to thank Cathy Campbell, Flora Cornish, Morten Skovdal, and members of the workshop on “Local–global dimensions of the fight against HIV/AIDS in low-income settings” held at London School of Economics, September 2010, for the initial invitation and subsequent helpful discussions. I owe thanks to all of the individuals who gave their time and insights to me during sometimes lengthy or multiple interviews, and to Derek Ambrosino and Lawrence Geiter for providing corrections and further thoughts on earlier drafts. Two anonymous reviewers provided excellent comments for which I am grateful. Funding for this research comes from a National Science Foundation Grant 1027285 .

Keywords

  • Development
  • Drugs
  • HIV
  • MDR-TB
  • PDPs
  • Tuberculosis

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