Abstract
A DNA tetrahedron is employed for efficient delivery of doxorubicin into drug-resistant breast cancer cells. The drug delivered with the DNA nanoconstruct is considerably cytotoxic, whereas free doxorubicin is virtually non-cytotoxic for the drug-resistant cells. Thus, the DNA tetrahedron, made of the inherently natural and biocompatible material, can be a good candidate for the drug carrier to overcome MDR in cancer cells.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2010-2012 |
| Number of pages | 3 |
| Journal | Chemical Communications |
| Volume | 49 |
| Issue number | 20 |
| DOIs | |
| State | Published - Feb 12 2013 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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