Driving the Way to Tuberculosis Elimination: The Essential Role of Fundamental Research

Christian Lienhardt, Alison M. Kraigsley, Christine F. Sizemore

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Tuberculosis has impacted human health for millennia. The World Health Organization estimated that, in 2014, 9.6 million people developed tuberculosis and 1.5 million people died from the disease. In May 2014, the World Health Assembly endorsed the new "End TB Strategy" that presents a pathway to tuberculosis elimination. The strategy outlines 3 areas of emphasis, one of which is intensified research and innovation. In this article we highlight the essential role for fundamental tuberculosis research in the future of tuberculosis diagnostics, treatment, and prevention. To maximize the impact of fundamental research, we must foster collaboration among all stakeholders engaged in tuberculosis research and control to facilitate open dialogue to assure that critical gaps in outcome-oriented science are identified and addressed. We present here a framework for future discussions among scientists, physicians, research and development specialists, and public health managers for the reinforcement of national and international strategies toward tuberculosis elimination.

Original languageEnglish (US)
Pages (from-to)370-375
Number of pages6
JournalClinical Infectious Diseases
Issue number3
StatePublished - Aug 1 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016 The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved.


  • biomedical
  • elimination
  • global health
  • research
  • tuberculosis


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