Donor Scoring System for Cadaveric Renal Transplantation

Scott L. Nyberg, Arthur J. Matas, Margaret Rogers, William S. Harmsen, Jorge A. Velosa, Timothy S. Larson, Mikel Prieto, Michael B. Ishitani, Sylvester Sterioff, Mark D. Stegall

Research output: Contribution to journalArticlepeer-review

70 Scopus citations

Abstract

We studied early renal function in 241 consecutive patients who received cadaveric renal transplants at two different transplantation centers (group 1, n=90; group 2, n=151). Univariate and multivariate analyses of data from group 1 showed a significant correlation between seven donor variables and early renal function after cadaveric renal transplantation. A scoring system was developed from these seven donor variables (cause of death, 0-6 points; history of hypertension, 0-6; final creatinine clearance before procurement, 0-6; age, 0-6; history of diabetes mellitus, 0-3; cold ischemia time, 0-3; and severity of renal artery plaque, 0-3). Data from group 2 were used to validate the donor scoring system and stratify cadaver kidneys on the basis of score: grade A, 0-5 points; grade B, 6-10; grade C, 11-15; and grade D, 16-32. A significant decline in early renal function was observed with increasing donor score and grade of cadaver kidney. In conclusion, a donor scoring system based on information available at the time of procurement can be used to estimate early graft function after cadaveric renal transplantation and may assist in the allocation of marginal organs.

Original languageEnglish (US)
Pages (from-to)162-170
Number of pages9
JournalAmerican Journal of Transplantation
Volume1
Issue number2
DOIs
StatePublished - Jul 2001

Keywords

  • Delayed graft function
  • Marginal donor
  • Organ allocation

Fingerprint

Dive into the research topics of 'Donor Scoring System for Cadaveric Renal Transplantation'. Together they form a unique fingerprint.

Cite this