Objective: To evaluate the relation between tubal ligation, change in menstrual cycle characteristics, and early follicular phase hormones. Design: Cross-sectional analysis of women 36-44 years of age. Setting: The greater Boston area. Patient(s): Nine hundred seventy-six premenopausal women with intact uteri. Intervention(s): A comparison of women with and without a history of tubal ligation. Main Outcome Measure(s): Menstrual and reproductive histories were self-reported. Early follicular phase blood samples were obtained to assess FSH, LH, and E 2. We compared menstrual cycle changes from the first 5 years after menarche with completion of the baseline questionnaire in women with and without a prior history of tubal ligation. Result(s): Cycle length, cycle regularity, menses length, flow volume, dysmenorrhea, and hormone levels were similar in women with and without a history of tubal ligation. However, among parous women with a history of cesarean section, those with a tubal ligation >5 years ago experienced a marginal increase in volume of menstrual flow compared with women with no tubal ligation history. Conclusion(s): We found no significant change in menstrual cycle characteristics or hormone levels in women with or without a history of tubal ligation. However, tubal ligation may have a modest effect on the change in menstrual flow volume over time among parous women with a history of cesarean section.
- Cesarean section
- Tubal ligation