Docosahexaenoic acid production of the marine microalga Isochrysis galbana cultivated on renewable substrates from food processing waste under CO2 enrichment

Hongli Zheng; Fengru Ge; Kunyan Song; Zixiang Yang; Jinmeng Li; Feng Yan; Xiaodan Wu; Qi Zhang; Yuhuan Liu; Roger Ruan

doi:10.1016/j.scitotenv.2022.157654

Docosahexaenoic acid production of the marine microalga Isochrysis galbana cultivated on renewable substrates from food processing waste under CO₂ enrichment

Hongli Zheng, Fengru Ge, Kunyan Song, Zixiang Yang, Jinmeng Li, Feng Yan, Xiaodan Wu, Qi Zhang, Yuhuan Liu, Roger Ruan

Bioproducts and Biosystems Engineering

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Leftover dough is a starch-rich food processing waste of Chinese steamed bread. Leftover dough hydrolysates enriched with glucose and amino acids were used to cultivate the marine microalga Isochrysis galbana to produce docosahexaenoic acid (DHA) under CO₂ enrichment. Isochrysis galbana could use mixed carbon sources (CO₂, glucose, and amino acids) synchronously to grow and accumulate DHA. Cell growth, the uptake of glucose and amino acids, and DHA production were significantly affected by CO₂ enrichment. The maximum biomass concentration of 3.85 g L⁻¹ was achieved with 3 % CO₂. And the maximum DHA yield was 65.5 mg L⁻¹ d⁻¹. To enhance DHA production, a two-stage cultivation strategy was successfully developed by this work. The maximum DHA yield of the two-stage culture was elevated by 2.3-fold. It is feasible to produce DHA by Isochrysis galbana using leftover dough under CO₂ enrichment.

Original language	English (US)
Article number	157654
Journal	Science of the Total Environment
Volume	848
DOIs	https://doi.org/10.1016/j.scitotenv.2022.157654
State	Published - Nov 20 2022

Bibliographical note

Funding Information:
This work was supported in part by grants from the National Natural Science Foundation of China (Grant Nos. 21767017 and 22066016 ), and Science and Technology Project of Jiangxi Provincial Department of Science and Technology (Grant Nos. 20192BBH80023 and 20212BDH81004 ).

Publisher Copyright:
© 2022 Elsevier B.V.

Keywords

CO enrichment
Docosahexaenoic acid
Food processing waste
Leftover dough
Microalga
Renewable substrates

PubMed: MeSH publication types

Journal Article

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10.1016/j.scitotenv.2022.157654

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@article{f9dcb0a3dc0e44a09cc0a223b92411f5,

title = "Docosahexaenoic acid production of the marine microalga Isochrysis galbana cultivated on renewable substrates from food processing waste under CO2 enrichment",

abstract = "Leftover dough is a starch-rich food processing waste of Chinese steamed bread. Leftover dough hydrolysates enriched with glucose and amino acids were used to cultivate the marine microalga Isochrysis galbana to produce docosahexaenoic acid (DHA) under CO2 enrichment. Isochrysis galbana could use mixed carbon sources (CO2, glucose, and amino acids) synchronously to grow and accumulate DHA. Cell growth, the uptake of glucose and amino acids, and DHA production were significantly affected by CO2 enrichment. The maximum biomass concentration of 3.85 g L−1 was achieved with 3 % CO2. And the maximum DHA yield was 65.5 mg L−1 d−1. To enhance DHA production, a two-stage cultivation strategy was successfully developed by this work. The maximum DHA yield of the two-stage culture was elevated by 2.3-fold. It is feasible to produce DHA by Isochrysis galbana using leftover dough under CO2 enrichment.",

keywords = "CO enrichment, Docosahexaenoic acid, Food processing waste, Leftover dough, Microalga, Renewable substrates",

author = "Hongli Zheng and Fengru Ge and Kunyan Song and Zixiang Yang and Jinmeng Li and Feng Yan and Xiaodan Wu and Qi Zhang and Yuhuan Liu and Roger Ruan",

note = "Funding Information: This work was supported in part by grants from the National Natural Science Foundation of China (Grant Nos. 21767017 and 22066016 ), and Science and Technology Project of Jiangxi Provincial Department of Science and Technology (Grant Nos. 20192BBH80023 and 20212BDH81004 ). Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",

year = "2022",

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day = "20",

doi = "10.1016/j.scitotenv.2022.157654",

language = "English (US)",

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T1 - Docosahexaenoic acid production of the marine microalga Isochrysis galbana cultivated on renewable substrates from food processing waste under CO2 enrichment

AU - Zheng, Hongli

AU - Ge, Fengru

AU - Song, Kunyan

AU - Yang, Zixiang

AU - Li, Jinmeng

AU - Yan, Feng

AU - Wu, Xiaodan

AU - Zhang, Qi

AU - Liu, Yuhuan

AU - Ruan, Roger

N1 - Funding Information: This work was supported in part by grants from the National Natural Science Foundation of China (Grant Nos. 21767017 and 22066016 ), and Science and Technology Project of Jiangxi Provincial Department of Science and Technology (Grant Nos. 20192BBH80023 and 20212BDH81004 ). Publisher Copyright: © 2022 Elsevier B.V.

PY - 2022/11/20

Y1 - 2022/11/20

N2 - Leftover dough is a starch-rich food processing waste of Chinese steamed bread. Leftover dough hydrolysates enriched with glucose and amino acids were used to cultivate the marine microalga Isochrysis galbana to produce docosahexaenoic acid (DHA) under CO2 enrichment. Isochrysis galbana could use mixed carbon sources (CO2, glucose, and amino acids) synchronously to grow and accumulate DHA. Cell growth, the uptake of glucose and amino acids, and DHA production were significantly affected by CO2 enrichment. The maximum biomass concentration of 3.85 g L−1 was achieved with 3 % CO2. And the maximum DHA yield was 65.5 mg L−1 d−1. To enhance DHA production, a two-stage cultivation strategy was successfully developed by this work. The maximum DHA yield of the two-stage culture was elevated by 2.3-fold. It is feasible to produce DHA by Isochrysis galbana using leftover dough under CO2 enrichment.

AB - Leftover dough is a starch-rich food processing waste of Chinese steamed bread. Leftover dough hydrolysates enriched with glucose and amino acids were used to cultivate the marine microalga Isochrysis galbana to produce docosahexaenoic acid (DHA) under CO2 enrichment. Isochrysis galbana could use mixed carbon sources (CO2, glucose, and amino acids) synchronously to grow and accumulate DHA. Cell growth, the uptake of glucose and amino acids, and DHA production were significantly affected by CO2 enrichment. The maximum biomass concentration of 3.85 g L−1 was achieved with 3 % CO2. And the maximum DHA yield was 65.5 mg L−1 d−1. To enhance DHA production, a two-stage cultivation strategy was successfully developed by this work. The maximum DHA yield of the two-stage culture was elevated by 2.3-fold. It is feasible to produce DHA by Isochrysis galbana using leftover dough under CO2 enrichment.

KW - CO enrichment

KW - Docosahexaenoic acid

KW - Food processing waste

KW - Leftover dough

KW - Microalga

KW - Renewable substrates

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