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Docking of μ-conotoxin GIIIA in the sodium channel outer vestibule
Gaurav Choudhary
, Marcela P. Aliste
, D. Peter Tieleman
, Robert J. French
,
Samuel C. Dudley
Medicine - Cardiology Division
Research output
:
Contribution to journal
›
Article
›
peer-review
49
Scopus citations
Overview
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Dive into the research topics of 'Docking of μ-conotoxin GIIIA in the sodium channel outer vestibule'. Together they form a unique fingerprint.
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Keyphrases
Sodium Channel
100%
Conotoxin
100%
Outer Vestibule
100%
P-loop
75%
High-affinity Binding
75%
Isoform Selectivity
50%
Channel Interaction
50%
Mutant Cycle Analysis
50%
Coupling Energy
50%
Molecular Dynamics Simulation
25%
Positively Charged
25%
Two-electrode Voltage Clamp
25%
Binding Selectivity
25%
Xenopus Oocytes
25%
Specific Interactions
25%
Charged Residue
25%
Vestibule
25%
High-affinity Ligands
25%
Double mutant Cycle
25%
Na+ Channel
25%
Voltage-gated Channels
25%
Interacting Residues
25%
Basic Side Chains
25%
Toxin Residues
25%
Biochemistry, Genetics and Molecular Biology
Conotoxin
100%
Sodium Channel
100%
Isoform
75%
Binding Affinity
75%
Voltage Clamp
25%
Electric Potential
25%
Xenopus
25%
Messenger RNA
25%
Alanine
25%