Do donor characteristics really matter? Short- and long-term impact of donor characteristics on recipient survival, 1995-1999

Jonathan M. Chen, Prashant Sinha, Hiranya A. Rajasinghe, Sanjeev J. Suratwala, Jonathan D. McCue, Matthew J. McCarty, Xzabia Caliste, Helen M. Hauff, Ranjit John, Niloo M. Edwards

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

We reviewed the impact of multiple donor characteristics on recipient mortality by univariate and multivariate analyses in a cohort of heart donors from 1995 to 1999. A sub-cohort of donors was also selected who met "marginal" criteria, and the early and late survival of these patients was then compared. Surrogates of donor size (donor weight, donor body mass index [BMI], BMI mismatch >20%), under-resuscitation (hematocrit, 24-hour fluid intake) and age >56 years were significantly associated with peri-operative mortality in the univariate analysis; in the multivariate analysis, only average donor heart rate at procurement (p = .001), donor hematocrit (p = .02) and donor weight (p = .05) were significantly associated. Few donor characteristics actually impact significantly on recipient outcome, and thus recipient characteristics may figure more prominently than those of the donor toward the risk of death after transplantation.

Original languageEnglish (US)
Pages (from-to)608-610
Number of pages3
JournalJournal of Heart and Lung Transplantation
Volume21
Issue number5
DOIs
StatePublished - 2002

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