Abstract
We present a theoretical study of the electrophoresis of DNA through a periodic array of narrow slits and deep wells (a nanofilter). We focus on the transport of short DNA under strong fields, showing that longer molecules travel faster due to a new mechanism "torque-assisted escape". This new prediction can lead to enhanced nanofluidic separations of DNA.
| Original language | English (US) |
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| Title of host publication | Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 |
| Editors | Jean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 997-999 |
| Number of pages | 3 |
| ISBN (Electronic) | 9780979806407 |
| State | Published - 2007 |
| Event | 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France Duration: Oct 7 2007 → Oct 11 2007 |
Publication series
| Name | Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 |
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Conference
| Conference | 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 |
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| Country/Territory | France |
| City | Paris |
| Period | 10/7/07 → 10/11/07 |
Bibliographical note
Publisher Copyright:© 2007 CBMS.
Keywords
- DNA Electrophoresis
- Nanofilters
- Nanofluidics
- Non-equilibrium transport