Abstract
Hold the water! Deep-eutectic solvents (DESs) are nonvolatile media suitable for a wide range of chemical reactions. The discovery that nucleic acids can form duplex, triplex, and G quadruplex structures (which in some cases differ from those adopted in aqueous media) in a water-free DES (see picture) opens the enticing possibility that catalytic nucleic acids and enzyme-nucleic acid complexes could also be used in these solvents.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6310-6314 |
| Number of pages | 5 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 49 |
| Issue number | 36 |
| DOIs | |
| State | Published - Aug 23 2010 |
Keywords
- DNA structures
- Ionic liquids
- Nucleic acids
- Solvent effects
- Sustainable chemistry
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