Diversity in the Chlamydia trachomatis histone homologue Hc2

Ted Hackstadt, Timothy J. Brickman, Clifton E. Barry, Janet Sager

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Chlamydia trachomatis elementary bodies contain two developmentally expressed histone H1 homologues. An 18-kDa histone homologue, Hc1, is conserved among C. trachomatis serovars and C. psittaci. The other histone homologue, Hc2 (encoded by hctB), varies in size between C. trachomatis serovars but is present in reduced amounts or absent from C. psittaci. The variation in Hc2 size among C. trachomatis serovars was found to be due to internal deletions from a region of the hctB gene encoding lysine- and alanine-rich pentameric repeats.

Original languageEnglish (US)
Pages (from-to)137-141
Number of pages5
Issue number1
StatePublished - Sep 30 1993

Bibliographical note

Copyright 2014 Elsevier B.V., All rights reserved.


  • Histone-like protein
  • intracellular parasite
  • nucleotide sequence
  • serovar


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