These studies determined the differential autoradiographic distribution of [125I]α-bungarotoxin versus [3H]nicotine relative to the histochemically defined perikarya for neurophysin and corticotropin releasing factor (CRF). Specific [3H]nicotine binding sites occured in relatively greater density within the neuropil surrounding PVN and SON compared to within the nuclei. In contrast, the highest density of [125I]α-BTX sites codistributed with neurophysin immunoreactive perikarya within these nuclei.
- Corticotropin releasing factor (CRF)
- Nicotic site