Distinguishing the viability of a single yeast cell with an ultra-sensitive radio frequency sensor

Yang Yang; Hanqiao Zhang; Junjie Zhu; Gaoyan Wang; Tzuen Rong Tzeng; Xiangchun Xuan; Kama Huang; Pingshan Wang

doi:10.1039/b921502f

Distinguishing the viability of a single yeast cell with an ultra-sensitive radio frequency sensor

Yang Yang, Hanqiao Zhang, Junjie Zhu, Gaoyan Wang, Tzuen Rong Tzeng, Xiangchun Xuan, Kama Huang, Pingshan Wang

Research output: Contribution to journal › Article › peer-review

101 Scopus citations

Abstract

We propose and demonstrate a simple, ultra sensitive radio frequency (RF) sensor to detect a single yeast cell and distinguish its viability in a microfluidic channel. On-chip interference is used to cancel background probing signals to improve sensor sensitivity. Individual viable and nonviable yeast cells (∼ 5.83 ± 0.85 μm in diameter) are measured with clear sensing and identification of these cells.

Original language	English (US)
Pages (from-to)	553-555
Number of pages	3
Journal	Lab on a chip
Volume	10
Issue number	5
DOIs	https://doi.org/10.1039/b921502f
State	Published - 2010
Externally published	Yes

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10.1039/b921502f

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abstract = "We propose and demonstrate a simple, ultra sensitive radio frequency (RF) sensor to detect a single yeast cell and distinguish its viability in a microfluidic channel. On-chip interference is used to cancel background probing signals to improve sensor sensitivity. Individual viable and nonviable yeast cells (∼ 5.83 ± 0.85 μm in diameter) are measured with clear sensing and identification of these cells.",

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AU - Yang, Yang

AU - Zhang, Hanqiao

AU - Zhu, Junjie

AU - Wang, Gaoyan

AU - Tzeng, Tzuen Rong

AU - Xuan, Xiangchun

AU - Huang, Kama

AU - Wang, Pingshan

PY - 2010

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AB - We propose and demonstrate a simple, ultra sensitive radio frequency (RF) sensor to detect a single yeast cell and distinguish its viability in a microfluidic channel. On-chip interference is used to cancel background probing signals to improve sensor sensitivity. Individual viable and nonviable yeast cells (∼ 5.83 ± 0.85 μm in diameter) are measured with clear sensing and identification of these cells.

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Distinguishing the viability of a single yeast cell with an ultra-sensitive radio frequency sensor

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