Distinct striatal regions support movement selection, preparation and execution

Emmanuel Gerardin, Jean Baptiste Pochon, Jean Baptiste Poline, Léon Tremblay, Pierre François Van De Moortele, Richard Levy, Bruno Dubois, Denis Le Bihan, Stéphane Lehéricy

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

The aim of this study was to determine whether distinct striatal territories are specifically involved during the selection, preparation and execution of a movement. Nine volunteers were studied using fMRI at 3 T. Subjects were presented with visual stimuli instructing them to prepare during a variable delay and then execute a button press with either the left or the right hand. The side of the movement was either freely selected by the subject (free selection) or specified by the instruction cue (preparation). Movement selection, preparation and execution were associated with activation in the caudate nucleus, the anterior and the posterior parts of the putamen, respectively. These results suggest that these three aspects of movement are represented within distinct basal ganglia regions.

Original languageEnglish (US)
Pages (from-to)2327-2331
Number of pages5
JournalNeuroreport
Volume15
Issue number15
DOIs
StatePublished - Oct 25 2004

Keywords

  • Basal ganglia
  • Functional MRI
  • Motor system

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