Distinct mechanisms of action of anti-CD154 in early versus late treatment of murine lupus nephritis

Keyphrases

• Abrogation 8%
• Autoantibody Production 16%
• Autoimmunity 8%
• CD154 100%
• CD40 8%
• Chemokines 8%
• Distinct Mechanism 100%
• Early Effect 8%
• Early Treatment 8%
• Early-late 100%
• Effector Phase 8%
• F1 Mice 8%
• Immune Complex Deposition 33%
• In Situ 8%
• Induction Period 8%
• Interleukin-10 8%
• Late Intervention 8%
• Late Treatment 100%
• Long-term Survival 8%
• Lupus 8%
• Lupus Nephritis 100%
• Mechanism of Action 100%
• Messenger RNA (mRNA) 8%
• Messenger RNA Expression 8%
• Murine Lupus 100%
• Nephritis 16%
• Production Complex 8%
• Proteinuria 8%
• Rapid Reduction 8%
• Remission 8%
• Renal Pathology 8%
• Therapeutic Agents 8%
• Tissue Damage 8%
• Transforming Growth Factor-β 8%
• Tumor Necrosis Factor-α 8%

Medicine and Dentistry

• Autoantibodies 50%
• Autoimmunity 25%
• Cancer Growth Factor 25%
• Chemokine 25%
• Cytokine 25%
• Diseases 50%
• Immune Complex Deposition 100%
• Interleukin 10 25%
• Long Term Survival 25%
• Lupus Erythematosus 50%
• Lupus Nephritis 100%
• Messenger RNA 50%
• Nephritic Syndrome 50%
• Proteinuria 25%
• Renal Pathology 25%
• Therapeutic Agent 25%
• Tissue Injury 25%
• Tumor Necrosis Factor 25%

Immunology and Microbiology

• Autoantibodies 16%
• Autoimmunity 8%
• Cancer Growth Factor 8%
• CD154 100%
• Chemokine 8%
• Cytokine 8%
• Immune Complex Deposition 33%
• Interleukin 10 8%
• Long Term Survival 8%
• Lupus Erythematosus 100%
• Nephritis 100%
• Ribonucleic Acid 16%
• Tumor Necrosis Factor 8%