Abstract
The prosencephalon forms at the end of primary neurulation as one of three principal vesicles: the hindbrain, midbrain, and forebrain (prosencephalon). The earliest disorder of prosencephalic formation, aprosencephaly-atelencephaly spectrum, is extremely rare. Major disorders of prosencephalic structures including holoprosencephaly, agenesis and hypoplasia of the corpus callosum, and septo-optic dysplasia, are described following a brief introduction to prosencephalic development.
| Original language | English (US) |
|---|---|
| Title of host publication | Swaiman's Pediatric Neurology |
| Subtitle of host publication | Principles and Practice |
| Publisher | Elsevier |
| Pages | 341-352.e4 |
| ISBN (Electronic) | 9780443109447 |
| ISBN (Print) | 9780443111068 |
| DOIs | |
| State | Published - Jan 1 2025 |
Bibliographical note
Publisher Copyright:© 2026 Elsevier Inc. All rights reserved.
Keywords
- cavus septum pellucidum
- corpus callosum
- Forebrain
- holoprosencephaly
- prosencephalon
- septo optic dysplasia
- SHH gene
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