Discriminative stimulus properties of phenytoin in the pigeon

Kathleen Krafft, James Cleary, Alan Poling

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Pigeons trained under a two-key drug discrimination procedure eventually learned to discriminate 5 mg/kg phenytoin from saline injections. When 1.25-20 mg/kg doses of phenytoin were substituted for the training dose, the percentage of responses directed to the phenytoin-appropriate key varied directly with dose. Chlorpromazine, d-amphetamine, diazepam, and phenobarbital failed to produce phenytoin-like patterns of responding.

Original languageEnglish (US)
Pages (from-to)82-83
Number of pages2
JournalPsychopharmacology
Volume79
Issue number1
DOIs
StatePublished - Jan 1 1983

Keywords

  • Chlorpromazine
  • Diazepam
  • Drugs as discriminative stimuli
  • Key-peck response
  • Phenobarbital
  • Phenytoin
  • Pigeons
  • d-Amphetamine

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