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Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action

  • Jozafina Milicaj
  • , Bakar A. Hassan
  • , Joy M. Cote
  • , Carlos A. Ramirez-Mondragon
  • , Nadiya Jaunbocus
  • , Angelika Rafalowski
  • , Kaelan R. Patel
  • , Colleen D. Castro
  • , Ramaiah Muthyala
  • , Yuk Y. Sham
  • , Erika A. Taylor

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science