Discovery of acylsulfonohydrazide-derived inhibitors of the lysine acetyltransferase, kat6a, as potent senescence-inducing anti-cancer agents

Daniel L. Priebbenow, David J. Leaver, Nghi Nguyen, Benjamin Cleary, H. Rachel Lagiakos, Julie Sanchez, Lian Xue, Fei Huang, Yuxin Sun, Prashant Mujumdar, Ramesh Mudududdla, Swapna Varghese, Silvia Teguh, Susan A. Charman, Karen L. White, David M. Shackleford, Kasiram Katneni, Matthew Cuellar, Jessica M. Strasser, Jayme L. DahlinMichael A. Walters, Ian P. Street, Brendon J. Monahan, Kate E. Jarman, Helene Jousset Sabroux, Hendrik Falk, Matthew C. Chung, Stefan J. Hermans, Natalie L. Downer, Michael W. Parker, Anne K. Voss, Tim Thomas, Jonathan B. Baell

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Chemistry

Pharmacology, Toxicology and Pharmaceutical Science