Directed Enzyme and Pathway Evolution

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
Original languageEnglish (US)
Title of host publicationEnzyme Technologies
Subtitle of host publicationMetagenomics, Evolution, Biocatalysis, and Biosynthesis
PublisherJohn Wiley and Sons
Number of pages35
ISBN (Print)9780470286241
StatePublished - May 25 2011


  • Directed enzyme and pathway evolution - and in vitro evolution of enzymes, whole-gene and site-directed random mutagenesis
  • Mutational robustness and protein evolvability - factor for success of a directed evolution experiment, selection of a suitable starting protein sequence(s)
  • Sophisticated analytical, modeling and genomics tools - genome sequencing efforts driving current efforts in metabolic engineering

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