Direct sequencing of the human microbiome readily reveals community differences

Justin Kuczynski, Elizabeth K. Costello, Diana R. Nemergut, Jesse Zaneveld, Christian L. Lauber, Dan Knights, Omry Koren, Noah Fierer, Scott T. Kelley, Ruth E. Ley, Jeffrey I. Gordon, Rob Knight

Research output: Contribution to journalReview article

113 Scopus citations

Abstract

Culture-independent studies of human microbiota by direct genomic sequencing reveal quite distinct differences among communities, indicating that improved sequencing capacity can be most wisely utilized to study more samples, rather than more sequences per sample.

Original languageEnglish (US)
Article number210
JournalGenome biology
Volume11
Issue number5
DOIs
StatePublished - May 5 2010

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    Kuczynski, J., Costello, E. K., Nemergut, D. R., Zaneveld, J., Lauber, C. L., Knights, D., Koren, O., Fierer, N., Kelley, S. T., Ley, R. E., Gordon, J. I., & Knight, R. (2010). Direct sequencing of the human microbiome readily reveals community differences. Genome biology, 11(5), [210]. https://doi.org/10.1186/gb-2010-11-5-210