Direct correlation among crystal structure, mechanical behaviour and tabletability in a trimorphic molecular compound

Partha Pratim Bag, Miles Chen, Changquan Calvin Sun, C. Malla Reddy

Research output: Contribution to journalArticlepeer-review

81 Scopus citations

Abstract

Powder compaction data of three polymorphic Forms I (shearing), II (bending) and III (brittle) of 6-chloro-2,4-dinitroaniline demonstrates a direct relationship among mechanical properties, crystal structure and tableting behaviour, showing the essence of structure based assessment of mechanical properties of crystals, e.g., for identifying more efficient API formulation and manufacture processes.

Original languageEnglish (US)
Pages (from-to)3865-3867
Number of pages3
JournalCrystEngComm
Volume14
Issue number11
DOIs
StatePublished - Jun 7 2012

Fingerprint

Dive into the research topics of 'Direct correlation among crystal structure, mechanical behaviour and tabletability in a trimorphic molecular compound'. Together they form a unique fingerprint.

Cite this