A dipole lattice model for lipid membranes and their interactions with peptides is presented. It uses the Langevin dipole method to calculate electrostatic interactions in the heterogenous membrane environment. A series of test cases are presented, including spherical charges, dipoles, side chain analogs, and helical peptides. The model consistently produces qualitatively correct results. (C) 2000 Wiley-Liss, Inc.
|Original language||English (US)|
|Number of pages||13|
|Journal||Proteins: Structure, Function and Genetics|
|State||Published - Nov 1 2000|