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Diphlorethohydroxycarmalol inhibits interleukin-6 production by regulating NF-κB, STAT5 and SOCS1 in lipopolysaccharide-stimulated RAW264.7 cells
Na Jin Kang
, Sang Chul Han
,
Gyeoung Jin Kang
, Dong Hwan Koo
, Young Sang Koh
, Jin Won Hyun
, Nam Ho Lee
, Mi Hee Ko
, Hee Kyoung Kang
, Eun Sook Yoo
Medicine - Cardiology Division
Research output
:
Contribution to journal
›
Article
›
peer-review
47
Scopus citations
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Dive into the research topics of 'Diphlorethohydroxycarmalol inhibits interleukin-6 production by regulating NF-κB, STAT5 and SOCS1 in lipopolysaccharide-stimulated RAW264.7 cells'. Together they form a unique fingerprint.
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Keyphrases
Nuclear factor-κB
100%
Interleukin-6
100%
Lipopolysaccharide
100%
RAW264.7 Cells
100%
SOCS1
100%
Diphlorethohydroxycarmalol
100%
Tumor Necrosis Factor-α
28%
RAW264.7 Macrophages
28%
Anti-inflammatory Effect
14%
Mechanism of Action
14%
Phosphorylation
14%
Effect Mechanism
14%
Anti-inflammatory Activity
14%
Signaling Molecules
14%
Janus Kinase 2 (JAK2)
14%
Negative Feedback
14%
Phenylalanine
14%
Inflammation Response
14%
Nuclear Translocation
14%
JAK2 Inhibitor
14%
Tosylate
14%
Janus Kinase-signal Transducer
14%
Brown Algae
14%
Chloromethyl Ketones
14%
Feedback Regulators
14%
Phlorotannins
14%
Pharmacology, Toxicology and Pharmaceutical Science
Lipopolysaccharide
100%
Interleukin 6
100%
Suppressor of Cytokine Signaling 1
100%
Tumor Necrosis Factor
40%
Antiinflammatory Activity
20%
Brown Alga
20%
Tosyl
20%
Inflammation
20%
Phenylalanine
20%
JAK-STAT Signaling
20%