Dimensionality reduction methods for extracting functional networks from large-scale CRISPR screens

Keyphrases

• Functional Networks 100%
• Dimensionality Reduction 100%
• CRISPR Interference (CRISPRi) 100%
• Dependency Map 100%
• Onion 66%
• Whole Genome 33%
• Mitochondria 33%
• Human Cell Lines 33%
• Cancer-specific 33%
• Functional Relationship 33%
• Principal Coordinate Analysis (PCoA) 33%
• Normalization Method 33%
• Normalized Data 33%
• Robust Principal Component Analysis 33%
• Single Network 33%
• Functional Phenotype 33%
• Unsupervised Dimensionality Reduction 33%
• Functional Gene Network 33%
• CRISPR-Cas9 Screen 33%
• Benchmarking Analysis 33%
• Cancer Dependency 33%
• Normalization Tools 33%
• Reduction-free Normalization 33%
• Genetic Dependency 33%

Biochemistry, Genetics and Molecular Biology

• Dimensionality Reduction 100%
• CRISPR 100%
• Principal Component Analysis 66%
• Genetics 33%
• Gene Network 33%
• CRISPR/Cas9 33%
• Mitochondrion 33%