Abstract
Diffusion imaging is a critical component in the pursuit of developing a better understanding of the human brain. Recent technical advances promise enabling the advancement in the quality of data that can be obtained. In this review the context for different approaches relative to the Human Connectome Project are compared. Significant new gains are anticipated from the use of high-performance head gradients. These gains can be particularly large when the high-performance gradients are employed together with ultrahigh magnetic fields. Transmit array designs are critical in realizing high accelerations in diffusion-weighted (d)MRI acquisitions, while maintaining large field of view (FOV) coverage, and several techniques for optimal signal-encoding are now available. Reconstruction and processing pipelines that precisely disentangle the acquired neuroanatomical information are established and provide the foundation for the application of deep learning in the advancement of dMRI for complex tissues. Level of Evidence: 3. Technical Efficacy Stage: Stage 3.
Original language | English (US) |
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Pages (from-to) | 36-57 |
Number of pages | 22 |
Journal | Journal of Magnetic Resonance Imaging |
Volume | 54 |
Issue number | 1 |
Early online date | Jun 20 2020 |
DOIs | |
State | Published - Jun 20 2020 |
Bibliographical note
Funding Information:Grant funding NIH P41 EB027061, NIH U01-EB025144, and NSF CAREER CCF-1651825
Funding Information:
Grant funding NIH P41 EB027061, NIH U01‐EB025144, and NSF CAREER CCF‐1651825 1
Publisher Copyright:
© 2020 International Society for Magnetic Resonance in Medicine
Keywords
- diffusion imaging
- human connectome project
- ultra high field
PubMed: MeSH publication types
- Journal Article
- Research Support, N.I.H., Extramural
- Research Support, U.S. Gov't, Non-P.H.S.
- Review