Diffuse large B-cell lymphoma of the colon--a rare presentation

Arpit Rao, Appalanaidu Sasapu, Shahanawaz Jiwani, Jonathan Laryea, Issam Makhoul

Research output: Contribution to journalArticlepeer-review


Patients with diffuse large B-cell lymphoma (DLBCL) can present with nodal or extra-nodal disease. The most common extra-nodal site is the gastrointestinal tract, including the stomach or illeo-cecal region. Primary colonic diffuse large B-cell lymphoma (DLBCL) is uncommon and presents a unique diagnostic and therapeutic challenge. We present a case of a middle-aged man who presented with abdominal pain and pathological weight loss and underwent hemi-colectomy for suspected adenocarcinoma. Final pathology revealed DLBCL, completely changing the prognosis and subsequent management. We will discuss some of the aspects of this rare presentation and shed light on therapeutic strategies currently available.

Original languageEnglish (US)
Pages (from-to)208-210
Number of pages3
JournalThe Journal of the Arkansas Medical Society
Issue number10
StatePublished - Mar 1 2015
Externally publishedYes


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