Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging

Seyedmehdi Payabvash; Kaan Meric; Zuzan Cayci

doi:10.1016/j.clinimag.2015.09.001

Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging

Seyedmehdi Payabvash
, Kaan Meric
, Zuzan Cayci

Radiology

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Purpose: To differentiate malignant from benign cervical lymph nodes in patients with head/neck cancer. Methods: In this retrospective study, 39 patients with primary head/neck cancer who underwent Positron Emission Tomography (PET)/Computerized Tomography (CT) and image-guided lymph node biopsy were included. Results: Overall, 23 (59%) patients had biopsy-proven malignant cervical lymphadenopathy. Malignant lymph nodes had higher maximum standardized uptake (SUV-max) value (P<. 001) and short-axis diameter (P= 015) compared to benign nodes. An SUV-max of ≥. 2.5 was 100% sensitive, and an SUV-max ≥. 5.5 was 100% specific for malignant lymphadenopathy. Conclusion: The PET/CT SUV-max value can help with differentiation of malignant cervical lymph nodes in patients with head/neck cancer.

Original language	English (US)
Pages (from-to)	101-105
Number of pages	5
Journal	Clinical Imaging
Volume	40
Issue number	1
DOIs	https://doi.org/10.1016/j.clinimag.2015.09.001
State	Published - Jun 22 2015

Keywords

CT
Lymphadenopathy
Maximum standardized uptake value
Neck cancer
Positron emission tomography

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.clinimag.2015.09.001

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@article{17011634e3294edfbd18af93cb69816c,

title = "Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging",

abstract = "Purpose: To differentiate malignant from benign cervical lymph nodes in patients with head/neck cancer. Methods: In this retrospective study, 39 patients with primary head/neck cancer who underwent Positron Emission Tomography (PET)/Computerized Tomography (CT) and image-guided lymph node biopsy were included. Results: Overall, 23 (59\%) patients had biopsy-proven malignant cervical lymphadenopathy. Malignant lymph nodes had higher maximum standardized uptake (SUV-max) value (P<. 001) and short-axis diameter (P= 015) compared to benign nodes. An SUV-max of ≥. 2.5 was 100\% sensitive, and an SUV-max ≥. 5.5 was 100\% specific for malignant lymphadenopathy. Conclusion: The PET/CT SUV-max value can help with differentiation of malignant cervical lymph nodes in patients with head/neck cancer.",

keywords = "CT, Lymphadenopathy, Maximum standardized uptake value, Neck cancer, Positron emission tomography",

author = "Seyedmehdi Payabvash and Kaan Meric and Zuzan Cayci",

year = "2015",

month = jun,

day = "22",

doi = "10.1016/j.clinimag.2015.09.001",

language = "English (US)",

volume = "40",

pages = "101--105",

journal = "Clinical Imaging",

issn = "0899-7071",

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TY - JOUR

T1 - Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging

AU - Payabvash, Seyedmehdi

AU - Meric, Kaan

AU - Cayci, Zuzan

PY - 2015/6/22

Y1 - 2015/6/22

N2 - Purpose: To differentiate malignant from benign cervical lymph nodes in patients with head/neck cancer. Methods: In this retrospective study, 39 patients with primary head/neck cancer who underwent Positron Emission Tomography (PET)/Computerized Tomography (CT) and image-guided lymph node biopsy were included. Results: Overall, 23 (59%) patients had biopsy-proven malignant cervical lymphadenopathy. Malignant lymph nodes had higher maximum standardized uptake (SUV-max) value (P<. 001) and short-axis diameter (P= 015) compared to benign nodes. An SUV-max of ≥. 2.5 was 100% sensitive, and an SUV-max ≥. 5.5 was 100% specific for malignant lymphadenopathy. Conclusion: The PET/CT SUV-max value can help with differentiation of malignant cervical lymph nodes in patients with head/neck cancer.

AB - Purpose: To differentiate malignant from benign cervical lymph nodes in patients with head/neck cancer. Methods: In this retrospective study, 39 patients with primary head/neck cancer who underwent Positron Emission Tomography (PET)/Computerized Tomography (CT) and image-guided lymph node biopsy were included. Results: Overall, 23 (59%) patients had biopsy-proven malignant cervical lymphadenopathy. Malignant lymph nodes had higher maximum standardized uptake (SUV-max) value (P<. 001) and short-axis diameter (P= 015) compared to benign nodes. An SUV-max of ≥. 2.5 was 100% sensitive, and an SUV-max ≥. 5.5 was 100% specific for malignant lymphadenopathy. Conclusion: The PET/CT SUV-max value can help with differentiation of malignant cervical lymph nodes in patients with head/neck cancer.

KW - CT

KW - Lymphadenopathy

KW - Maximum standardized uptake value

KW - Neck cancer

KW - Positron emission tomography

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DO - 10.1016/j.clinimag.2015.09.001

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Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging

Abstract

Keywords

UN SDGs

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