Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging

Seyedmehdi Payabvash, Kaan Meric, Zuzan Cayci

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Purpose: To differentiate malignant from benign cervical lymph nodes in patients with head/neck cancer. Methods: In this retrospective study, 39 patients with primary head/neck cancer who underwent Positron Emission Tomography (PET)/Computerized Tomography (CT) and image-guided lymph node biopsy were included. Results: Overall, 23 (59%) patients had biopsy-proven malignant cervical lymphadenopathy. Malignant lymph nodes had higher maximum standardized uptake (SUV-max) value (P<. 001) and short-axis diameter (P= 015) compared to benign nodes. An SUV-max of ≥. 2.5 was 100% sensitive, and an SUV-max ≥. 5.5 was 100% specific for malignant lymphadenopathy. Conclusion: The PET/CT SUV-max value can help with differentiation of malignant cervical lymph nodes in patients with head/neck cancer.

Original languageEnglish (US)
Pages (from-to)101-105
Number of pages5
JournalClinical Imaging
Volume40
Issue number1
DOIs
StatePublished - Jun 22 2015

Keywords

  • CT
  • Lymphadenopathy
  • Maximum standardized uptake value
  • Neck cancer
  • Positron emission tomography

Fingerprint Dive into the research topics of 'Differentiation of benign from malignant cervical lymph nodes in patients with head and neck cancer using PET/CT imaging'. Together they form a unique fingerprint.

Cite this